- This is the sixth successive year that a MotoGP event has been held at the Austin circuit.
- In total, there have been 30 previous Grand Prix events hosted in the USA: Daytona – 2, Laguna Seca – 15, Indianapolis – 8 and Austin – 5.
- Marc Marquez has won on each of the nine occasions that he has raced in the MotoGP class in America; five times at Austin, three times at Indianapolis and at Laguna Seca in 2013. Only once in these nine appearances in MotoGP in America has Marquez not been on pole; at Laguna Seca in 2013 when he qualified in second place on the grid behind Stefan Bradl.
- The only riders currently competing in the MotoGP class who have won in the class at any of the American circuits are: Valentino Rossi, Dani Pedrosa, Jorge Lorenzo and Marc Marquez.
- Honda riders have won the last fourteen MotoGP races in the USA; the last non-Honda MotoGP winner in the USA was Jorge Lorenzo, at Laguna Seca in 2010 on a Yamaha.
- Honda riders have qualified on pole for the last ten MotoGP races in the USA. The last non-Honda rider to start from pole at any of the US circuits is Jorge Lorenzo at Laguna Seca in 2012.
- Prior to last year Ducati had one rider finish on the podium in Austin for three successive years: Andrea Dovizioso was third in 2014 and second in 2015; Andrea Iannone was third in 2016. Last year the first Ducati rider across the line was Dovizioso in sixth place.
- The second place finishes of Jorge Lorenzo in 2016 and Valentino Rossi last year are the best results for Yamaha at the Austin circuit.
- After his second place finish in Austin last year Valentino Rossi headed the championship classification for the first time since he arrived at the final race of 2015 at Valencia with a seven point lead over Jorge Lorenzo.
- Maverick Viñales fourth place finish two years ago is the best result for Suzuki at the Austin circuit.
- All fifteen podium finishers in the five previous MotoGP races held at Austin have been riders from either Spain of Italy.
- Eleventh place finisher in Austin last year, Jonas Folger, crossed the line just 18.903 seconds behind race winner Marc Marquez – this is the closest top eleven of the MotoGP era.
- The three riders who finished on the podium in the Moto2 race last year in Austin (Morbidelli, Luthi and Nakagami) have all moved up to race in the MotoGP class in 2018.
- Three of the five Moto2 race winners in Austin are now competing in the MotoGP class: Alex Rins, Maverick Viñales and Franco Morbidelli. Sam Lowes, who won in Austin in 2015, is the only rider currently competing in Moto2 who has won in the class at this circuit.