- Last year Marc Marquez won at Brno by a margin of 12.438 seconds from team-mate Dani Pedrosa. This is the largest margin of victory by Marquez in the MotoGP class.
- At the Czech Grand Prix Marc Marquez is scheduled to make his 100th Grand Prix start in the MotoGP class. At the age of just 25 years and 169 days Marquez is the second youngest ever rider to reach the milestone of 100 starts in the premier-class. The only rider to reach this milestone at a younger age is John Hopkins who was 24 years 348 days old when he made his 100th premier-class start at the Chinese GP in 2008.
- Pol Espargaro’s ninth place finish last year at Brno was the first top ten finish in the MotoGP class for KTM.
- The two riders with most grand prix victories at the current Brno circuit, each with seven wins, are Max Biaggi (4 x 250cc, 2 x 500cc, 1 x MotoGP) and Valentino Rossi (1x 125cc, 1 x 250cc, 1 x 500cc, 4 x MotoGP).
- Valentino Rossi is the only rider to win the MotoGP race at Brno in successive years – in 2008 and 2009.
- The best result for a Czech rider in the MotoGP class at Brno is 9th for Karel Abraham in 2012 riding a Ducati.
- When Valentino Rossi lines up on the grid at Brno it will be the 23rd successive year that he will have started in a grand prix race at Brno, and will be just the second circuit, along with Jerez, he will have raced in every year of his grand prix career. The other three circuits that have appeared on the grand prix schedule every year whilst Rossi has been racing (Mugello, Catalunya and Assen) were all circuits he did not start following his accident in practice for the Italian Grand Prix in 2010.
- Cal Crutchlow’s win at Brno in 2016 was the first victory in the premier-class by a British rider for thirty-five years since Barry Sheene riding a Yamaha in the 500cc Swedish Grand Prix at Anderstorp on 16th August 1981.